SP2 Products

Antibodies
SP2 Antibody
SP2 Antibody
NBP1-83054
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SP2 Antibody
SP2 Antibody
NBP1-67998
Species: Hu, Mu
Applications: WB, ELISA
Host: Rabbit Polyclonal
SP2 Antibody
SP2 Antibody
H00006668-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
SP2 Overexpression Lysate (Na ...
SP2 Overexpression Lysate (Native)
NBP2-08037
Applications: WB
SP2 Overexpression Lysate (De ...
SP2 Overexpression Lysate (Denatured)
H00006668-T01
Applications: WB
Proteins
SP2 Partial Recombinant Prote ...
SP2 Partial Recombinant Protein
H00006668-Q01
Species: Hu
Applications: WB, ELISA, PA
SP2 Recombinant Protein
SP2 Recombinant Protein
H00006668-P01
Species: Hu
Applications: WB, ELISA, PA
SP2 Recombinant Protein Antig ...
SP2 Recombinant Protein Antigen
NBP1-83054PEP
Species: Hu
Applications: AC
RNAi
SP2 RNAi
SP2 RNAi
H00006668-R01
Species: Hu

Description

The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4 (SPR-1). Sp transcription factors share similar structures but do not share similar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus. Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes. Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not. Sp2 only weakly binds to GT boxes. Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues. Sp1 and Sp3, but not Sp2 or Sp4, interact with E2, a regulatory element for the b4 subunit of neuronal nicotinic acetylcholine receptors. Sp3 is the only Sp member to inhibit Sp1 and Sp4 mediated transcription. The gene3 encoding human Sp2 maps to chromosome 17p32.3.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 6668
Alternate Names
  • transcription factor Sp2
  • KIAA0048
  • Sp2 transcription factor

Bioinformatics Tool for SP2

Discover related pathways, diseases and genes to SP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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