SOX14 Products

Description

SOX14 is a 36 kDa protein that belongs to the SOX (SRY-related HMG-box) family of transcription factors. It plays a crucial role in the development and differentiation of the central nervous system and is critically involved in the regulation of embryogenesis, neural differentiation, and the development of specific neuronal populations. Aberrant expression or mutations of SOX14 have been associated with developmental disorders, including speech and cognitive impairments, as well as various cancers such as medulloblastoma and glioblastoma where it impacts cell proliferation, migration, and survival pathways. SOX14 is also essential for proper neural crest cell development and is implicated in neural tube defects when dysregulated. This makes it an important biomarker for neurological development and related pathologies.

Bioinformatics

Uniprot	O95416 Mouse
Product By Gene ID	8403
Alternate Names	HMG box transcription factor SOX-14 MGC119898 MGC119899 SOX14 SOX28 SRY (sex determining region Y)-box 14 SRY-box 14 transcription factor SOX-14