SODD/BAG4 Products

Antibodies
SODD/BAG4 Antibody
SODD/BAG4 Antibody
NB100-56696
Species: Hu
Applications: WB, Flow
Host: Rabbit Polyclonal
SODD/BAG4 Antibody
SODD/BAG4 Antibody
NB100-56464
Species: Hu, Mu, Rt, Bv, Ca, Pm
Applications: WB
Host: Rabbit Polyclonal
SODD/BAG4 Antibody
SODD/BAG4 Antibody
NBP2-27329
Species: Hu
Applications: WB, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
SODD/BAG4 Overexpression Lysa ...
SODD/BAG4 Overexpression Lysate (D...
H00009530-T01
Species: Hu
Applications: WB
SODD/BAG4 Overexpression Lysa ...
SODD/BAG4 Overexpression Lysate (N...
NBL1-07902
Applications: WB
Proteins
Recombinant Human SODD/BAG4 P ...
Recombinant Human SODD/BAG4 Protein
H00009530-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human SODD/BAG4 P ...
Recombinant Human SODD/BAG4 Protein
H00009530-P02
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human SODD/BAG4 P ...
Recombinant Human SODD/BAG4 Protein
H00009530-P01
Species: Hu
Applications: WB, ELISA, PA

Description

Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 9530
Alternate Names
  • Silencer of death domains
  • BAG-family molecular chaperone regulator-4
  • Bcl-2-associated athanogene 4
  • SODDBAG family molecular chaperone regulator 4
  • BAG-4
  • BCL2-associated athanogene 4

Research Areas for SODD/BAG4

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Tumor Suppressors

PTMs for SODD/BAG4

Learn more about PTMs related to SODD/BAG4.

Phosphorylation

Bioinformatics Tool for SODD/BAG4

Discover related pathways, diseases and genes to SODD/BAG4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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