SMAD1/5/8/9 Products

Antibodies
SMAD1/5/8/9 Antibody
SMAD1/5/8/9 Antibody
NB100-56656
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
SMAD1/5/8/9 Antibody
SMAD1/5/8/9 Antibody
NB600-962
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
SMAD1/5/8/9 Antibody
SMAD1/5/8/9 Antibody
NB100-56443
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal

Description

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily (1). SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8 and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. Human SMAD1 is a 465 amino acid protein; GenBank Accession No. AAP36050.1. Human SMAD2 is a 467 amino acid protein; GenBank Accession No. AAC51918.1 Human SMAD3 is a 425 amino acid protein; GenBank Accession No. NP_005893.1 Human SMAD4 is a 552 amino acid protein GenBank Accession No. NP_005350.1. Human SMAD5 is a 465 amino acid protein; GenBank Accession No. AAC50791.1. Human SMAD6 is a 496 amino acid protein; GenBank Accession No. AAH12986.1 Human SMAD7 is a 426 amino acid protein; GenBank Accession No. AAB81354.1 Mouse SMAD8 is a 430 amino acid protein; GenBank Accession No. AAN85445.1 Human SMAD9 is a 430 amino acid protein; GenBank Accession No. NP_005896.1

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 4086
Alternate Names
  • Smad1
  • Mad-related protein 1
  • transforming growth factor-beta signaling protein 1
  • MAD homolog 1
  • TGF-beta signaling protein 1
  • hSMAD1
  • SMAD, mothers against DPP homolog 1
  • BSP1
  • mothers against decapentaplegic homolog 1
  • BSP-1
  • mothers against decapentaplegic homolog 1
  • Mothers against DPP homolog 1
  • MADH1JV41
  • JV4-1SMAD, mothers against DPP homolog 1 (Drosophila)
  • MADR1MAD, mothers against decapentaplegic homolog 1 (Drosophila)
  • SMAD family member 1SMAD 1

Research Areas for SMAD1/5/8/9

Find related products by research area and learn more about each of the different research areas below.

Cancer
Diabetes Research

Bioinformatics Tool for SMAD1/5/8/9

Discover related pathways, diseases and genes to SMAD1/5/8/9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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