SLC9A7 Products

Antibodies
SLC9A7 Antibody
SLC9A7 Antibody
NBP2-13347
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
SLC9A7 Antibody
SLC9A7 Antibody
NBP1-00945
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
SLC9A7 Antibody
SLC9A7 Antibody
NBP1-79719
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Proteins
SLC9A7 Recombinant Protein An ...
SLC9A7 Recombinant Protein Antigen
NBP2-13347PEP
Species: Hu
Applications: AC
RNAi
SLC9A7 RNAi
SLC9A7 RNAi
H00084679-R01
Species: Hu

Description

Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH (pHi) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. NHE7 (human 725 aa, chromosome Xp11.4) is ubiquitously expressed, and predominantly localizes to the trans-golgi network. NHE7 mediates the influx of Na+ or K+ in exchange for H+. It is ~70% related to NHE6 but relatively less (~25%) homologous with other NHEs.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 84679
Alternate Names
  • solute carrier family 9 (sodium/hydrogen exchanger)
  • Na(+)/H(+) exchanger 7
  • sodium/hydrogen exchanger 7
  • NHE-7
  • nonselective sodium potassium/proton exchanger
  • Solute carrier family 9 member 7
  • NHE7SLC9A6
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 7
  • solute carrier family 9 (sodium/hydrogen exchanger), member 7

Pathways for SLC9A7

View related products by pathway and learn more about each of the pathways below.

Cell Adhesion
Localization
Ion Homeostasis
Reverse Transcription
Cation Homeostasis
Cellular Ion Homeostasis

Bioinformatics Tool for SLC9A7

Discover related pathways, diseases and genes to SLC9A7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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