Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
Sodium/calcium-potassium exchanger proteins (NCKX1) have been reported to occur in retinal photoreceptors and in brain (NCKX2). Unlike the abundant and widely expressed sodium/calcium exchanger which catalyzes the exchange of 3 sodium ions for 1 calcium ion to modulate intracellular calcium levels, NCKX isoforms exchange 4 sodium ions for 1 calcium and 1 potassium ion. The sodium/calcium-potassium exchanger uses the transmembrane sodium gradient to catalyze countertransport of calcium in a potassium-dependent mechanism against its electrochemical gradient. It is hypothesized that NCKX2 plays a significant role in calcium homeostasis and the regulation of neuronal function.
|Product By Gene ID
- retinal cone Na-Ca+K exchanger
- solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Pathways for SLC24A2
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Bioinformatics Tool for SLC24A2
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