SLC16A3 Products

Antibodies
SLC16A3 Antibody
SLC16A3 Antibody
Species: Hu, Rt, Mouse
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Proteins
SLC16A3 Recombinant Protein A ...
SLC16A3 Recombinant Protein Antigen
NBP1-81251PEP
Species: Hu
Applications: AC
SLC16A3 Recombinant Protein
SLC16A3 Recombinant Protein
H00009123-G01
Species: Hu
RNAi
SLC16A3 RNAi
SLC16A3 RNAi
H00009123-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs),which function as proton symports and are stereoselective for L-lactate.The MCT family consists of at least eight members, MCT1-8, which contain between 10-12 transmembrane-helical (TM) domains, with the amino and carboxy termini located in the cytoplasm. MCT1 is widely expressed and is the major form of MCTs in tumor cells and erythrocytes. MCT2 is highly expressed in liver and testis, while MCT3 and MCT4 are predominantly expressed in skeletal muscle.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 9123
Alternate Names
  • Solute carrier family 16 member 3
  • monocarboxylate transporter 4
  • Monocarboxylate transporter 3
  • MGC138474
  • solute carrier family 16 (monocarboxylic acid transporters), member 3
  • MCT4MGC138472
  • MCT3MCT 4
  • MCT 3
  • solute carrier family 16, member 3 (monocarboxylic acid transporter 4)

PTMs for SLC16A3

Learn more about PTMs related to SLC16A3.

Carboxylation
Methylation
Demethylation

Bioinformatics Tool for SLC16A3

Discover related pathways, diseases and genes to SLC16A3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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