SIAH1/2 Products

SIAH1/2 Antibody (8G7H12)
SIAH1/2 Antibody (8G7H12)
Species: Hu, Rt, Po, Dr, Ze, Mu(-)
Applications: WB, IP
Host: Mouse Monoclonal


The Drosophila SINA (seven in absentia) protein is an E3 ubiquitin ligase component of the RAS signal transduction pathway. The RAS signal pathway controls cell proliferation, differentiation, and survival, and regulation of this pathway is critical for normal development. In Drosophila, SINA serves as a downstream gatekeeper required for proper RAS signal transduction. Similarly to SINA in Drosophila, the human protein SIAH has also been shown to be required for oncogenic RAS signaling in cancer.


Entrez Human
Product By Gene ID 6477
Alternate Names
  • EC 6.3.2
  • siah-1
  • Seven in absentia homolog 1
  • E3 ubiquitin-protein ligase SIAH1
  • Siah-1a
  • SIAH1A
  • Siah-1
  • FLJ08065
  • EC 6.3.2.-
  • hSIAH1
  • siah-1a
  • seven in absentia homolog 1 (Drosophila)

Research Areas for SIAH1/2

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Ubiquitin Proteasome Pathway

Bioinformatics Tool for SIAH1/2

Discover related pathways, diseases and genes to SIAH1/2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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