SARS2 Products

Description

This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

Bioinformatics

Product By Gene ID	54938
Alternate Names	EC 6.1.1.11 FLJ20450 mitochondrial seryl-tRNA synthetase mtSerRS SARS serine tRNA ligase 2, mitochondrial Serine--tRNA ligase serine-tRNA ligase, mitochondrial SerRS SerRSmtSARSM SERS seryl-tRNA synthetase 2 seryl-tRNA synthetase 2, mitochondrial seryl-tRNA synthetase, mitochondrial Seryl-tRNA(Ser/Sec) synthetase SYS

Research Areas for SARS2

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism