SAP18 Products

Description

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.

Bioinformatics

Entrez	10284 Human
Uniprot	AAH30836 Human NM_005870 Human NP_005861 Human
Product By Gene ID	10284
Alternate Names	2HOR0202cell growth inhibiting protein 38 Cell growth-inhibiting gene 38 protein cell growth-inhibiting protein 38 histone deacetlyase complex subunit SAP18 histone deacetylase complex subunit SAP18,18 kDa Sin3-associated polypeptide MGC27131 SAP18p SAP18P Sin3A-associated protein, 18kDa Sin3-associated polypeptide p18 sin3-associated polypeptide, 18 kDa sin3-associated polypeptide, p18

Research Areas for SAP18

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Stem Cell Markers