SAP18 Products

Description

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.

Bioinformatics

Entrez	10284 Human
Uniprot	NP_005861 Human NM_005870 Human AAH30836 Human
Product By Gene ID	10284
Alternate Names	sin3-associated polypeptide, p18 SAP18p sin3-associated polypeptide, 18 kDa histone deacetylase complex subunit SAP18,18 kDa Sin3-associated polypeptide Sin3-associated polypeptide p18 histone deacetlyase complex subunit SAP18 Cell growth-inhibiting gene 38 protein cell growth-inhibiting protein 38 MGC27131 2HOR0202cell growth inhibiting protein 38 SAP18P Sin3A-associated protein, 18kDa

Diseases related to SAP18

Discover more about diseases related to SAP18.

Atypical Small Acinar Proliferation Of The Prostate Gland
Carcinoma
Neoplasms
Retinoblastoma
Basal Cell Carcinoma
Pallister-hall Syndrome
Maple Syrup Urine Disease
Teratocarcinoma
Malignant Tumor Of Cervix
Coinfection
Tumor Angiogenesis
Medulloblastoma
Mycoses
Ectopic Tissue
Neurofibrillary Tangles
Rubinstein-taybi Syndrome
Infective Disorder
Salivary Gland Diseases
Kyphosis Deformity Of Spine
Basal Cell Nevus Syndrome

Pathways for SAP18

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Mrna Processing
Rna Interference
Embryo Development
Mrna Splicing
Reverse Transcription
Cell Cycle
Histone Deacetylation
Cell Death
Cell Growth
Transport
Cell Adhesion
Gene Silencing
Programmed Cell Death
Nuclear Export
Macroautophagy
Translation
Cell Differentiation
Gonad Development
Chromatin Remodeling
Cell Proliferation

Research Areas for SAP18

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Stem Cell Markers

PTMs for SAP18

Learn more about PTMs related to SAP18.

Deacetylation
Phosphorylation
Cleavage
Acetylation

Bioinformatics Tool for SAP18

Discover related pathways, diseases and genes to SAP18. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.