SAP102 Products

Antibodies
SAP102 Antibody (S19-2)
SAP102 Antibody (S19-2)
NBP1-21672
Species: Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
SAP102 Antibody
SAP102 Antibody
NBP1-87691
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
SAP102 Antibody
SAP102 Antibody
NB100-2063
Species: Mu, Rt
Applications: WB, IHC, IHC-Fr
Host: Rabbit Polyclonal
Lysates
SAP102 Overexpression Lysate ...
SAP102 Overexpression Lysate (Native)
NBL1-09910
Applications: WB
SAP102 Overexpression Lysate ...
SAP102 Overexpression Lysate (Dena...
H00001741-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human SAP102 Prot ...
Recombinant Human SAP102 Protein
H00001741-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human SAP102 Prot ...
Recombinant Human SAP102 Protein
H00001741-P01
Species: Hu
Applications: WB, ELISA, PA
SAP102 Recombinant Protein An ...
SAP102 Recombinant Protein Antigen
NBP2-58864PEP
Species: Hu
Applications: AC
RNAi
SAP102 RNAi
SAP102 RNAi
H00001741-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
SAP102 RNAi
SAP102 RNAi
H00001741-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Synapse-Associated Protein 102 (SAP102) is one of a family of plasma membrane-associated proteins found in synaptic junctions. Like other members of the family, SAP102 has three ~90 amino acid repeats called PDZ domains followed by an SH3 domain and a yeast guanylate kinase homology (GuK) domain. It is hypothesized that PDZ-domain interactions play a role in receptor and channel clustering which contributes to neuronal plasticity. SAP102 is believed to participate in the clustering of certain proteins, including NMDA receptors, shaker-type potassium channels at the synaptic membrane in CNS neurons. NMDA receptors and Shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with SAP102 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with SAP102 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Rat
Product By Gene ID 1741
Alternate Names
  • Neuroendocrine-DLG
  • Synapse-associated protein 102
  • neuroendocrine-DLG
  • SAP-102
  • NEDLGdisks large homolog 3
  • MRX90MRX
  • KIAA1232discs, large homolog 3 (neuroendocrine-dlg, Drosophila)
  • SAP102NE-Dlg
  • XLMR
  • discs, large homolog 3 (Drosophila)

Research Areas for SAP102

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Neuroscience

PTMs for SAP102

Learn more about PTMs related to SAP102.

Palmitoylation
Phosphorylation
Methylation

Bioinformatics Tool for SAP102

Discover related pathways, diseases and genes to SAP102. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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