SAFB Products

Antibodies
SAFB Antibody
SAFB Antibody
NB100-2593
Species: Hu, Mu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SAFB Antibody (5A11)
SAFB Antibody (5A11)
H00006294-M04
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Proteins
SAFB Partial Recombinant Prot ...
SAFB Partial Recombinant Protein
H00006294-Q01
Species: Hu
Applications: WB, ELISA, PA
SAFB Recombinant Protein Anti ...
SAFB Recombinant Protein Antigen
NBP1-83266PEP
Species: Hu
Applications: AC
SAFB Recombinant Protein Anti ...
SAFB Recombinant Protein Antigen
NBP1-83265PEP
Species: Hu
Applications: AC
RNAi
SAFB RNAi
SAFB RNAi
H00006294-R01
Species: Hu

Description

SAFB encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Product By Gene ID 6294
Alternate Names
  • scaffold attachment factor B1
  • HSP27 ERE-TATA-binding protein
  • Hsp27 ERE-TATA binding protein
  • SAF-B1
  • heat-shock protein (HSP27) estrogen response element and TATA box-bindingprotein
  • SAF-B
  • glutathione S-transferase fusion protein
  • HAP
  • SAFB1SAB-B1
  • HETDKFZp779C1727
  • HSP27 estrogen response element-TATA box-binding protein
  • scaffold attachment factor B

Research Areas for SAFB

Find related products by research area and learn more about each of the different research areas below.

DNA Repair

PTMs for SAFB

Learn more about PTMs related to SAFB.

Phosphorylation
Sumoylation
Deacetylation
Cleavage
Ubiquitination

Bioinformatics Tool for SAFB

Discover related pathways, diseases and genes to SAFB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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