RhoGAP Products

Antibodies
RhoGAP Antibody
RhoGAP Antibody
NBP2-20158
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
RhoGAP Antibody
RhoGAP Antibody
NBP2-58620
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
RhoGAP Antibody
RhoGAP Antibody
NBP2-14308
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
RhoGAP Overexpression Lysate ...
RhoGAP Overexpression Lysate (Native)
NBL1-07671
Applications: WB
Proteins
RhoGAP Recombinant Protein An ...
RhoGAP Recombinant Protein Antigen
NBP2-14308PEP
Species: Hu
Applications: AC
RhoGAP Recombinant Protein An ...
RhoGAP Recombinant Protein Antigen
NBP2-58620PEP
Species: Hu
Applications: AC
RNAi
RhoGAP RNAi
RhoGAP RNAi
H00000394-R02
Species: Hu
Applications: RNAi, RNAi SP
RhoGAP RNAi
RhoGAP RNAi
H00000394-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The p190 Rho GTPase activating protein RhoGAP) family includes two closely related proteins, p190-A and p190-B. p190-B contains an N-terminal GTPase domain and a C-terminal Rho-GAP domain (1). p190-B can be directly phosphorylated on a single identified tyrosine residue by the activated insulin and IGF-1 receptors. This phosphorylation causes p190-B to translocate to the lipid rafts of the plasma membrane, where it can facilitate the inactivation of the Rho GTPase. P190-B also has been shown to be tyrosine phosphorylated by c-Src and v-Src. Additionall; the GAP domain of p190-B as shown to attenuate signal-transducing activity of Rac, Rho and CDC42 (2-3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 394
Alternate Names
  • Rho-type GTPase-activating protein 5
  • rho GTPase-activating protein 5
  • p190BRhoGAP
  • p105 RhoGAP
  • growth factor independent 2
  • p100 RasGAP-associated p105 protein
  • RhoGAP5
  • p190-BGFI2
  • RHOGAP5
  • Rho GTPase activating protein 5

PTMs for RhoGAP

Learn more about PTMs related to RhoGAP.

Phosphorylation
Dephosphorylation
Cleavage
Amidation
Ribosylation

Bioinformatics Tool for RhoGAP

Discover related pathways, diseases and genes to RhoGAP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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