RelB Products

Antibodies
RelB Antibody (315206) [Uncon ...
RelB Antibody (315206) [Unconjugated]
MAB2698
Species: Hu
Applications: WB, IHC, ICC
Host: Mouse Monoclonal
RelB Antibody
RelB Antibody
NBP2-20123
Species: Hu, Mu
Applications: WB, ChIP, IHC, IHC-P, IP
Host: Rabbit Polyclonal
RelB Antibody
RelB Antibody
NBP2-34064
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
RelB Overexpression Lysate (N ...
RelB Overexpression Lysate (Native)
NBP2-10407
Applications: WB
RelB Overexpression Lysate (D ...
RelB Overexpression Lysate (Denatu...
H00005971-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human RelB Protei ...
Recombinant Human RelB Protein
H00005971-P01
Species: Hu
Applications: WB, ELISA, PA
RelB Recombinant Protein Anti ...
RelB Recombinant Protein Antigen
NBP2-34064PEP
Species: Hu
Applications: AC
RNAi
RelB RNAi
RelB RNAi
H00005971-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

RelB, also known as I-Rel, is a member of the Rel transcription factor family which also include; RelA-p65, c-Rel, NF-kB1 p100/52 and NF-kB2 p105/50 (1). Unlike other Rel-related protein, RelB does not bind to DNA or to inhibitor IkB, but is instead sequestered in the cytoplasm by precursor p100. Once p100 is processed, the p52/RelB complex translocates into the nucleus (2). RelB is also the transcription factor that has been associated most directly with dendritic cells (DCs) differentiation and function (3). It is upregulated and translocated into the nuclei of DC in response to various stimuli. RelB is also essential for generating a specific DC subset (CD11c+/CD11b+/CD8-/Dec205-) from hematopoietic stem cells (5).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 5971
Alternate Names
  • I-REL
  • I-Rel
  • IREL
  • nuclear factor of kappalight polypeptide gene enhancer in B-cells 3
  • v-rel reticuloendotheliosis viral oncogene homolog B

Research Areas for RelB

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific

Bioinformatics Tool for RelB

Discover related pathways, diseases and genes to RelB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related RelB Blog Posts

Check out the latest blog posts on RelB.
NFkB and p62 Both Activate and Regulate Inflammation
Nuclear factor kappa-light-chain-enhancer of activated B cells (NFkB) is a protein complex that regulates DNA transcription and is a critical regulator of cell survival. NFkB has long been known as a primer of inflammation, however researchers are...    Read more.
RelA/NF-kB - A proinflammatory signaling pathway with roles in immunity and cancer
The inflammatory response consists of a complex network of signaling pathways that regulate a diverse set of cytokines, growth factors, adhesion molecules, and transcription factors (1). Of the proinflammatory signaling pathways the NF-kB family is...    Read more.
Read more RelB related blogs.