RC74 Products

Antibodies
RC74 Antibody - BSA Free
RC74 Antibody - BSA Free
NBP2-58713
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
RC74 Antibody - BSA Free
RC74 Antibody - BSA Free
NBP2-57534
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
RC74 Antibody - BSA Free
RC74 Antibody - BSA Free
NBP2-20114
Species: Hu, Mu, Bv, Ch
Applications: WB
Host: Rabbit Polyclonal
Lysates
RC74 Overexpression Lysate
RC74 Overexpression Lysate
NBL1-12012
Species: Hu
Applications: WB
Proteins
Recombinant Human RC74 GST (N ...
Recombinant Human RC74 GST (N-Term...
H00055756-P01
Species: Hu
Applications: WB, ELISA, MA, AP
RC74 Recombinant Protein Anti ...
RC74 Recombinant Protein Antigen
NBP2-57534PEP
Species: Hu
Applications: AC
RC74 Recombinant Protein Anti ...
RC74 Recombinant Protein Antigen
NBP2-58713PEP
Species: Hu
Applications: AC

Description

Formation of the mature 3' ends of the vast majority of cellular mRNAs occurs through cleavage and polyadenylation and requires a cleavage and polyadenylation specificity factor (CPSF) containing, among other proteins, CPSF-73 and CPSF-100. RC-74 is an exclusively nuclear protein found in HeLa cells that has similar characteristics to CPSF-100. Like the complex that forms between CPSF-100 and CPSF-73, studies show that RC-74 may form a similar complex with RC-68 that is independent from the CPSF complex. This RC-68 / RC-74 complex may be involved in a pre-mRNA processing event other than cleavage and polyadenylation, such as the 3' end processing of a distinct subset of cellular pre-mRNAs encoding proteins required for G(1) progression and entry into S phase.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 55756
Alternate Names
  • CPSF2L
  • FLJ10871
  • Int9
  • INT9
  • integrator complex subunit 9
  • Protein related to CPSF subunits of 74 kDa
  • RC74
  • RC-74