RASGRP 4 Products

Antibodies
RASGRP 4 Antibody (1F3)
RASGRP 4 Antibody (1F3)
H00115727-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
RASGRP 4 Antibody (6D3)
RASGRP 4 Antibody (6D3)
H00115727-M02
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
RASGRP 4 Antibody
RASGRP 4 Antibody
H00115727-D01P
Species: Hu
Applications: WB, ELISA, PLA
Host: Rabbit Polyclonal
Lysates
RASGRP 4 Overexpression Lysat ...
RASGRP 4 Overexpression Lysate (De...
H00115727-T01
Species: Hu
Applications: WB
RASGRP 4 Overexpression Lysat ...
RASGRP 4 Overexpression Lysate (Na...
NBP2-05215
Applications: WB
Proteins
RASGRP 4 Partial Recombinant ...
RASGRP 4 Partial Recombinant Protein
H00115727-Q01
Species: Hu
Applications: WB, ELISA, PA
RASGRP 4 Recombinant Protein
RASGRP 4 Recombinant Protein
H00115727-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
RASGRP 4 RNAi
RASGRP 4 RNAi
H00115727-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

RASGRP 4 is encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Mouse
Product By Gene ID 115727
Alternate Names
  • RAS guanyl-releasing protein 4
  • guanyl nucleotide releasing protein 4
  • RAS guanyl releasing protein 4

Research Areas for RASGRP 4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for RASGRP 4

Learn more about PTMs related to RASGRP 4.

Phosphorylation

Bioinformatics Tool for RASGRP 4

Discover related pathways, diseases and genes to RASGRP 4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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