PTPN3 Products

Description

The protein encoded by the PTPN3 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Bioinformatics

Entrez	5774 Human
Uniprot	NM_002829 Human P26045 Human
Product By Gene ID	5774
Alternate Names	DKFZp686N0569 EC 3.1.3.48 protein tyrosin phosphatase H1 protein tyrosine phosphatase, non-receptor type 3 Protein-tyrosine phosphatase H1 PTP-H1 PTPH1cytoskeletal-associated protein tyrosine phosphatase tyrosine phosphatase tyrosine-protein phosphatase non-receptor type 3