In immature T cells the T-cell receptor beta-chain gene (TCRB; MIM 186930) is rearranged and expressed before the TCRA(MIM 186880) chain. At this early stage, TCRB can associate with the pre-T-cell receptor alpha chain (PTCRA). ThePTCRA, together with TCRB and the CD3 complex (see MIM 186740), minimally make up the pre-T cell receptor (pre-TCR),which regulates early T cell development.(supplied by OMIM)
|Product By Gene ID
- pre T-cell antigen receptor alpha
PTMs for PTCRA
Learn more about PTMs related to PTCRA.Methylation
Bioinformatics Tool for PTCRA
Discover related pathways, diseases and genes to PTCRA. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.