PTBP1 Products

Antibodies
PTBP1 Antibody (3H8)
PTBP1 Antibody (3H8)
H00005725-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P, IP
Host: Mouse Monoclonal
PTBP1 Antibody
PTBP1 Antibody
NB100-1310
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
PTBP1 Antibody
PTBP1 Antibody
NBP2-19996
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
PTBP1 Antibody Pair
PTBP1 Antibody Pair
H00005725-PW1
Species: Hu
Applications: WB, IP
Lysates
PTBP1 Overexpression Lysate ( ...
PTBP1 Overexpression Lysate (Denat...
H00005725-T01
Species: Hu
Applications: WB
PTBP1 Overexpression Lysate ( ...
PTBP1 Overexpression Lysate (Native)
NBL1-14918
Applications: WB
PTBP1 Overexpression Lysate ( ...
PTBP1 Overexpression Lysate (Native)
NBL1-14919
Applications: WB
Proteins
Recombinant Human PTBP1 Prote ...
Recombinant Human PTBP1 Protein
H00005725-P02
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human PTBP1 Prote ...
Recombinant Human PTBP1 Protein
H00005725-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human PTBP1 Prote ...
Recombinant Human PTBP1 Protein
H00005725-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
PTBP1 RNAi
PTBP1 RNAi
H00005725-R02
Species: Hu
Applications: RNAi, RNAi SP
PTBP1 RNAi
PTBP1 RNAi
H00005725-R03
Species: Hu
Applications: RNAi, RNAi SP
PTBP1 RNAi
PTBP1 RNAi
H00005725-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

PTBP1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 5725
Alternate Names
  • RNA-binding protein
  • polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoproteinI)
  • polypyrimidine tract-binding protein 1
  • pPTB
  • heterogeneous nuclear ribonucleoprotein polypeptide I
  • PTB4
  • PTB-T
  • PTB3
  • MGC8461
  • PTB2
  • MGC10830
  • PTB-1
  • HNRNPI
  • HNRPI
  • hnRNP I
  • HNRNP-I
  • PTB57 kDa RNA-binding protein PPTB-1
  • Heterogeneous nuclear ribonucleoprotein I
  • polypyrimidine tract binding protein 1

PTMs for PTBP1

Learn more about PTMs related to PTBP1.

Phosphorylation
Cleavage
Biotinylation
Acetylation

Bioinformatics Tool for PTBP1

Discover related pathways, diseases and genes to PTBP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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