PSMC3 Products

Antibodies
PSMC3 Antibody (9F3)
PSMC3 Antibody (9F3)
Species: Hu, Ca
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
PSMC3 Antibody
PSMC3 Antibody
NBP1-86962
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P, IF
Host: Rabbit Polyclonal
PSMC3 Antibody
PSMC3 Antibody
NBP1-32749
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PSMC3 Overexpression Lysate ( ...
PSMC3 Overexpression Lysate (Native)
NBL1-14888
Applications: WB
PSMC3 Overexpression Lysate ( ...
PSMC3 Overexpression Lysate (Denat...
H00005702-T01
Applications: WB
Proteins
PSMC3 Partial Recombinant Pro ...
PSMC3 Partial Recombinant Protein
H00005702-Q01
Species: Hu
Applications: WB, ELISA, PA
PSMC3 Recombinant Protein
PSMC3 Recombinant Protein
H00005702-P01
Species: Hu
Applications: WB, ELISA, PA
PSMC3 Recombinant Protein Ant ...
PSMC3 Recombinant Protein Antigen
NBP1-86962PEP
Species: Hu
Applications: AC
RNAi
PSMC3 RNAi
PSMC3 RNAi
H00005702-R02
Species: Hu

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq]

Bioinformatics

Entrez Human
Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5702
Alternate Names
  • human immunodeficiency virus tat transactivator binding protein-1
  • Proteasome subunit P50
  • MGC8487
  • Proteasome 26S subunit ATPase 3
  • TBP-126S protease regulatory subunit 6A
  • TBP1Tat-binding protein 1
  • proteasome (prosome, macropain) 26S subunit, ATPase, 3,26S proteasome AAA-ATPase subunit RPT5

PTMs for PSMC3

Learn more about PTMs related to PSMC3.

Ubiquitination
Phosphorylation
Sumoylation
Biotinylation
Acetylation

Bioinformatics Tool for PSMC3

Discover related pathways, diseases and genes to PSMC3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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