PSMB5 Products

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longest protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID

5693

Alternate Names

LMPX LMPXproteasome beta 5 subunit Macropain epsilon chain MB1 MB1EC 3.4.25.1 Multicatalytic endopeptidase complex epsilon chain proteasome (prosome, macropain) subunit, beta type, 5 proteasome catalytic subunit 3 Proteasome chain 6 Proteasome epsilon chain proteasome subunit beta type-5 Proteasome subunit MB1 Proteasome subunit X proteasome subunit, beta type, 5 PSMB5 PSX large multifunctional protease X XMGC104214

Research Areas for PSMB5

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Stem Cell Markers