PSMA7 Products

Antibodies
PSMA7 Antibody (1A10-3G12)
PSMA7 Antibody (1A10-3G12)
H00005688-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
PSMA7 Antibody (3F11)
PSMA7 Antibody (3F11)
Species: Hu
Applications: WB, Flow, IHC, IHC-P
Host: Mouse Monoclonal
PSMA7 Antibody
PSMA7 Antibody
NBP1-33539
Species: Hu, Mu, Bovine, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
PSMA7 Antibody Pair
PSMA7 Antibody Pair
H00005688-PW2
Species: Hu
Applications: WB, IP
PSMA7 Antibody Pair
PSMA7 Antibody Pair
H00005688-PW1
Species: Hu
Applications: WB, IP
Lysates
PSMA7 Overexpression Lysate ( ...
PSMA7 Overexpression Lysate (Native)
NBL1-14875
Applications: WB
PSMA7 Overexpression Lysate ( ...
PSMA7 Overexpression Lysate (Denat...
H00005688-T01
Applications: WB
Proteins
PSMA7 Recombinant Protein Ant ...
PSMA7 Recombinant Protein Antigen
NBP2-13819PEP
Species: Hu
Applications: AC
PSMA7 Recombinant Protein
PSMA7 Recombinant Protein
NBC1-22917
Species: Hu
Applications: PAGE
Host: Human
RNAi
PSMA7 RNAi
PSMA7 RNAi
H00005688-R01
Species: Hu

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5688
Alternate Names
  • Proteasome subunit XAPC7
  • proteasome subunit alpha type-7
  • Proteasome subunit RC6-1
  • proteasome subunit alpha 4
  • XAPC7
  • RC6-1
  • C6
  • HSPCMGC3755
  • EC 3.4.25.1
  • proteasome (prosome, macropain) subunit, alpha type, 7

Research Areas for PSMA7

Find related products by research area and learn more about each of the different research areas below.

Cancer
Core ESC-Like Genes
Hypoxia
Stem Cell Markers

PTMs for PSMA7

Learn more about PTMs related to PSMA7.

Phosphorylation
Cleavage
Methylation
Ubiquitination

Bioinformatics Tool for PSMA7

Discover related pathways, diseases and genes to PSMA7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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