PSF2 Products

Description

PSF2, also known as DNA replication complex GINS protein PSF2, is a 185 amino acid protein that is 21 kDa, belongs to the GINS2/PSF2 family, localizes in the nucleus, plays an essential role in the initiation of DNA replication and progression of DNA replication forks, and seems to bind preferentially to single-stranded DNA. This protein is being studied for its involvement in breast cancer. The protein has been also linked to the unwinding of DNA, S Phase, DNA strand elongation, synthesis of DNA, DNA replication, cell cycle, and cell cycle, mitotic pathways where it interacts with CHEK2, GINS4, FANCF, GTF2A1L, KPNA4, LMNB1, and other proteins.

Bioinformatics

Entrez	51659 Human
Uniprot	NM_016095 Human AAH03186 Human Q9Y248 Human Q53G08 Human
Product By Gene ID	51659
Alternate Names	GINS complex subunit 2 DNA replication complex GINS protein PSF2 HSPC037 PSF2Pfs2 GINS complex subunit 2 (Psf2 homolog)

Diseases related to PSF2

Discover more about diseases related to PSF2.

Malignant Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Mammary Neoplasms
Fanconi Anemia
Neoplasm Metastasis
Cell Transformation, Neoplastic
Hereditary Diseases
Endoreduplication
Anemia
Genomic Instability
Polyploidy
Aneuploidy
Pancytopenia
Dystrophy
Autistic Disorder
Cerebrovascular Accident
Gilles De La Tourette Syndrome
Migraine Disorders
Muscular Dystrophy

Pathways for PSF2

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Dna Replication
Cell Proliferation
Dna Repair
Hypersensitivity
Cell Growth
Response To Dna Damage Stimulus
Localization
Cytokinesis

Research Areas for PSF2

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Cell Cycle and Replication

Bioinformatics Tool for PSF2

Discover related pathways, diseases and genes to PSF2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.