PSD93 Products

Antibodies
PSD93 Antibody
PSD93 Antibody
NBP1-88088
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PSD93 Antibody (S18-30)
PSD93 Antibody (S18-30)
NBP2-12912
Species: Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
PSD93 Antibody
PSD93 Antibody
NB300-546
Species: Rt
Applications: WB, ICC/IF, IHC, IHC-Fr
Host: Rabbit Polyclonal
Lysates
PSD93 Overexpression Lysate ( ...
PSD93 Overexpression Lysate (Native)
NBP2-11069
Applications: WB
Proteins
PSD93 Recombinant Protein Ant ...
PSD93 Recombinant Protein Antigen
NBP1-88088PEP
Species: Hu
Applications: AC
RNAi
PSD93 RNAi
PSD93 RNAi
H00001740-R02
Species: Hu
Applications: RNAi, RNAi SP
PSD93 RNAi
PSD93 RNAi
H00283225-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Post Synaptic Density 93 (PSD 93), also known as chapsyn-110, is one of a family of plasma membrane-associated proteins found in synaptic junctions. PSD 93 is unique among family members in its expression in Purkinje neuron cell bodies and dendrites. PSD 93 has three ~90 amino acid repeats called PDZ domains, a single interior SH3 domain, and a carboxyl-terminal guanylate kinase homology (GuK) domain that is enzymatically inactive. It is hypothesized that PDZ-domain interactions play a role in receptor and channel clustering which contributes to neuronal plasticity.PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Product By Gene ID 1740
Alternate Names
  • DKFZp781E0954
  • Chapsyn-110
  • DKFZp781D1854
  • disks large homolog 2
  • discs, large homolog 2, chapsyn-110 (Drosophila)
  • discs, large homolog 2, chapsyn-110
  • Postsynaptic density protein PSD-93
  • PSD93,110kDa
  • MGC131811
  • PSD-93
  • FLJ37266
  • discs, large homolog 2 (Drosophila)

Research Areas for PSD93

Find related products by research area and learn more about each of the different research areas below.

Neuronal Cell Markers
Neuroscience
Neurotransmission
Vision

PTMs for PSD93

Learn more about PTMs related to PSD93.

Palmitoylation
Phosphorylation
Cleavage
Dephosphorylation

Bioinformatics Tool for PSD93

Discover related pathways, diseases and genes to PSD93. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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