PPAN Products

Description

PPAN is encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. This gene was found to cotranscript with P2RY11/P2Y(11), an immediate downstream gene on the chromosome that encodes a ATP receptor. The chimeric transcripts of this gene and P2RY11 were found to be ubiquitously present and regulated during granulocytic differentiation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Entrez	56342 Human
Uniprot	NM_020230 Human
Product By Gene ID	56342
Alternate Names	Peter Pan homolog MGC45852 Ssf-1 MGC14226 suppressor of SWI4 1 homolog peter pan (Drosophila) homolog suppressor of sterile four 1 Brix domain-containing protein 3 second-step splicing factor 1 SSF2 homolog of S. cerevisiae SSF1 SSF SSF1BXDC3SSF-1 peter pan homolog (Drosophila)

Diseases related to PPAN

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Neoplasms
Cell Transformation, Neoplastic
Liver Carcinoma
Acute Promyelocytic Leukemia
Leukemia
Crest Syndrome
Carcinoma

Pathways for PPAN

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Cell Growth
Cell Proliferation
Dna Replication
Ribosome Biogenesis
Cell Death
Cell Migration
Larval Development
Regulation Of Gene Expression
Cartilage Development
Cell Division
Pronephros Development
Mrna Splicing
Response To Atp
Mating
Rrna Processing

PTMs for PPAN

Learn more about PTMs related to PPAN.

Cleavage

Bioinformatics Tool for PPAN

Discover related pathways, diseases and genes to PPAN. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.