POLR2J2 Products

Description

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq]

Bioinformatics

Product By Gene ID	246721
Alternate Names	DNA directed RNA polymerase II polypeptide J-related DNA-directed RNA polymerase II subunit RPB11-b1 HRPB11B MGC105050 MGC54043 polymerase (RNA) II (DNA directed) polypeptide J2 RNA polymerase II subunit B11-b1 RPB11 RPB11b1DNA-directed RNA polymerase II subunit J2