Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Description
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic molecules. PLCis subdivided into beta, gamma, delta, epsilon, zeta and eta subtypes, which catalyze the hydrolysis ofphosphatidylinositol 4,5-bisphosphate (PIP2) to inositol 1,4,5-trisphosphate (IP3) and 1,2-diacylglycerol (DAG). IP3and DAG both have important second messenger functions. PLC-beta is primarily activated by Gq/11 proteins andPLC-gamma is activated by phosphorylation in response to a variety of growth factor and immune system signals.Phospholipases are ubiquitously expressed and have diverse biological functions including roles in inflammation, cellgrowth, signaling and death and maintenance of membrane phospholipids.
Bioinformatics
| Entrez |
Human
|
| Product By Gene ID |
89869 |
| Alternate Names |
- MGC149685
- phosphoinositide phospholipase C-zeta-1
- phospholipase C, zeta 1
- PI-phospholipase C zeta 1
- PLCzeta
- PLC-zeta-1
- testis-development protein NYD-SP27
- testis-development related NYD-SP27
|
Research Areas for PLCZ1
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
