Phospholamban Products

Antibodies
Phospholamban Antibody (2D12) ...
Phospholamban Antibody (2D12)
NB300-582
Species: Hu, Mu, Rt, Po, Ca, Ch, GP, Rb, Sh
Applications: WB, IHC-P, IP, ICC, IF
Host: Mouse Monoclonal
Phospholamban Antibody
Phospholamban Antibody
NBP2-19807
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Phospholamban Antibody
Phospholamban Antibody
NBP1-85543
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
Phospholamban Partial Recombi ...
Phospholamban Partial Recombinant ...
H00005350-Q01
Species: Hu
Applications: WB, ELISA, PA
Phospholamban Recombinant Pro ...
Phospholamban Recombinant Protein ...
NBP1-85543PEP
Species: Hu
Applications: AC
RNAi
Phospholamban RNAi
Phospholamban RNAi
H00005350-R01
Species: Hu

Description

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1-25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25-52) is mostly hydrophobic, protease resistant and stabilizes the pentamer. Following adrenergic stimulation of cardiac muscle, PLB is phosphorylated at Ser16 and at Thr17 which is correlated with stimulation of calcium transport activity across the SR membrane and relaxation of cardiac fibers.

Bioinformatics

Uniprot Human
Human
Human
Canine
Product By Gene ID 5350
Alternate Names
  • CMD1PPLBcardiac phospholamban
  • phospholamban

Research Areas for Phospholamban

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction

Bioinformatics Tool for Phospholamban

Discover related pathways, diseases and genes to Phospholamban. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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