Species: Hu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Description
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. [provided by RefSeq]
Bioinformatics
| Product By Gene ID |
5207 |
| Alternate Names |
- 2-kinase:fructose-2,6-bisphosphatase
- 6PF-2-K/Fru-2,6-P2ase liver isozyme
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
- F6PK
- fructose-6-phosphate
- MGC116715,6PF-2-K/Fru-2,6-P2ase 1
- MGC116717
- PFK/FBPase 1
- PFRXHL2K
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