Periplakin Products

Antibodies
Periplakin Antibody
Periplakin Antibody
NBP2-19775
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Periplakin Antibody
Periplakin Antibody
NBP2-49306
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Periplakin Antibody
Periplakin Antibody
NB100-55264
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Proteins
Periplakin Recombinant Protei ...
Periplakin Recombinant Protein Ant...
NBP2-13795PEP
Species: Hu
Applications: AC
Periplakin Recombinant Protei ...
Periplakin Recombinant Protein Ant...
NBP2-49306PEP
Species: Hu
Applications: AC

Description

Peroplakin is a component of the cornified envelope of keratinocytes. It may link the cornified envelope to desmosomes and intermediate filaments and may act as a localization signal in PKB/AKT-mediated signaling. [from: http://www.genecards.org/cgi-bin/carddisp.pl®gene=PPL&search=Periplakin] Endogenous periplakin localizes to different cellular compartments, including plasma membrane, intermediate filament structures, the nucleus and mitochondria. Overexpression of the C-terminal part of periplakin, encompassing the PKB binding region, results in predominant intermediate filament localization and little nuclear staining. Periplakin is expressed in epithelial cells, together with envoplakin, the precursor of the epidermal cornified envelope. Furthermore, periplakin has been shown to be a target antigen in paraneoplastic pemphigus, and in keratinocytes it localizes at desmosomes and the interdesmosomal plasma membrane. [from: http://jcs.biologists.org/cgi/content/full/115/20/3957]

Bioinformatics

Uniprot Human
Product By Gene ID 5493
Alternate Names
  • MGC134872
  • KIAA0568
  • 195 kDa cornified envelope precursor protein
  • 190 kDa paraneoplastic pemphigus antigen
  • periplakin

Bioinformatics Tool for Periplakin

Discover related pathways, diseases and genes to Periplakin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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