PER1 Products

Antibodies
PER1 Antibody
PER1 Antibody
NBP2-24589
Species: Hu, Mu, Rt, Bv, Eq, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
PER1 Antibody
PER1 Antibody
Species: Hu, Mu, Rt, Dr, Ha
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
PER1 Antibody
PER1 Antibody
NBP2-24692
Species: Mu, Po, Bv, Ca, Eq
Applications: IHC-P
Host: Rabbit Polyclonal
Lysates
PER1 Overexpression Lysate (D ...
PER1 Overexpression Lysate (Denatu...
H00005187-T01
Species: Hu
Applications: WB
PER1 Overexpression Lysate (D ...
PER1 Overexpression Lysate (Denatu...
H00005187-T02
Species: Hu
Applications: WB
RNAi
PER1 RNAi
PER1 RNAi
H00005187-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Circadian rhythmicity is a basic property of phylogenetically diverse organisms which range from animals and plants, to fungi. Regulation of endogenous biological clocks is regulated at the genetic level by a protein-mediated, autoregulatory feed-back loop. In mammals, several genes that encode members of the basic helix-loop helix (bHLH) PAS (PER-ARNT-SIM) transcription factor family have been shown to play a significant role in regulating circadian oscillations. Transactivation of CLOCK-induced genes is mediated via an E box enhancer (CACGTG) found upstream of target genes. CLOCK-ARNT3 heterodimers bind to E box regulatory elements and stimulate gene transcription. CLOCK has been shown to transactivate the mammalian homolog of Drosophila per. PER, in concert with the product of the mammalian timeless gene (TIM), negatively regulates its own transcription by blocking the activity of the CLOCK-BMAL1 transactivation complex.

Bioinformatics

Uniprot Mouse
Product By Gene ID 5187
Alternate Names
  • KIAA0482
  • hPER1
  • Period, drosophila, homolog of
  • Circadian pacemaker protein Rigui
  • period circadian protein homolog 1
  • Circadian clock protein PERIOD 1
  • PERhPER
  • RIGUIMGC88021
  • period (Drosophila) homolog 1
  • period homolog 1 (Drosophila)

Research Areas for PER1

Find related products by research area and learn more about each of the different research areas below.

Circadian Rhythm
Neuroscience
Vision

Bioinformatics Tool for PER1

Discover related pathways, diseases and genes to PER1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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