PDE1C Products

Antibodies
PDE1C Antibody
PDE1C Antibody
NB300-672
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
PDE1C Antibody
PDE1C Antibody
NBP2-38666
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PDE1C Antibody
PDE1C Antibody
NB110-40465
Species: Hu, Mu, Rt, Bt, Bv, Ca, Eq, Ha, Mk, Pm, Rb
Applications: IHC-P
Host: Rabbit Polyclonal
Proteins
PDE1C Recombinant Protein Ant ...
PDE1C Recombinant Protein Antigen
NBP2-48555PEP
Species: Hu
Applications: AC
PDE1C Recombinant Protein Ant ...
PDE1C Recombinant Protein Antigen
NBP2-38666PEP
Species: Hu
Applications: AC

Description

PDE1C is a phosphodiesterase activated by the binding of calmodulin in the presence of calcium. Cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodiesterases. In mammals at least 11 different families of PDEs can be discriminated (PDE1-11) based on their kinetic properties and inhibition to various pharmacological agents. Three different PDE1 genes have been identified (PDE1A, PDE1B, PDE1C). The enzymes of the PDE1A and PDE1B have higher affinity for cGMP than for cAMP, where as, PDE1C has high affinity for both cAMP and cGMP. Calcium-Calmodulin stimulates the activity of each of these enzymes several-fold. The PDE1C gene codes a family of proteins (variants) that differ from each other at amino and carboxy termini of the protein. The tissue distribution of PDE1C is different from other PDE1 gene family members.

Bioinformatics

Uniprot Human
Human
Product By Gene ID 5137
Alternate Names
  • EC 3.1.4
  • calmodulin-dependent (70kD)
  • phosphodiesterase 1C, calmodulin-dependent 70kDa

PTMs for PDE1C

Learn more about PTMs related to PDE1C.

Phosphorylation
Reduction

Bioinformatics Tool for PDE1C

Discover related pathways, diseases and genes to PDE1C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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