PDE11A Products

Description

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Uniprot	NP_001070664.1 Human NP_001070665.1 Human NP_001070826.1 Human NP_058649 Human NP_058649.3 Human NP_058649.3 Human Q9HCR9 Human
Product By Gene ID	50940
Alternate Names	cAMP and cGMP cyclic nucleotide phosphodiesterase 11A cAMP and cGMP phosphodiesterase 11A cyclic nucleotide phosphodiesterase 11A dual 3'-5'-cyclic-AMP and -GMP phosphodiesterase 11A EC 3.1.4 EC 3.1.4.17 EC 3.1.4.35 FLJ23693 MGC133355 MGC133356 PDE11A1 PDE11A2 PDE11A3 phosphodiesterase 11A PPNAD2

Research Areas for PDE11A

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction