PCDHA8 Products

Antibodies
PCDHA8 Antibody
PCDHA8 Antibody
NBP2-30030
Species: Hu
Applications: WB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
PCDHA8 Antibody
PCDHA8 Antibody
NBP1-86195
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PCDHA8 Overexpression Lysate ...
PCDHA8 Overexpression Lysate (Dena...
H00056140-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human PCDHA8 Prot ...
Recombinant Human PCDHA8 Protein
H00056140-P01
Species: Hu
Applications: WB, ELISA, PA
PCDHA8 Recombinant Protein An ...
PCDHA8 Recombinant Protein Antigen
NBP1-86195PEP
Species: Hu
Applications: AC
RNAi
PCDHA8 RNAi
PCDHA8 RNAi
H00056140-R01
Species: Hu
Applications: RNAi, RNAi SP
PCDHA8 RNAi
PCDHA8 RNAi
H00056140-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

PCDHA8 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq]

Bioinformatics

Uniprot Human
Product By Gene ID 56140
Alternate Names
  • protocadherin alpha-8
  • KIAA0345-like 6
  • PCDH-ALPHA8
  • PCDH-alpha-8
  • protocadherin alpha 8

Diseases related to PCDHA8

Discover more about diseases related to PCDHA8.

Cell Transformation, Neoplastic
Malignant Neoplasms
Glioma
Brain Neoplasms

Pathways for PCDHA8

View related products by pathway and learn more about each of the pathways below.

Methylation
Dna Methylation
Pathogenesis

PTMs for PCDHA8

Learn more about PTMs related to PCDHA8.

Methylation

Bioinformatics Tool for PCDHA8

Discover related pathways, diseases and genes to PCDHA8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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