PCDH11Y Products

Description

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation. [provided by RefSeq]. Transcript Variant: This variant (c) includes exons 4, 5 and 7-9 and encodes an isoform (c) that shares its N terminus with isoform b and has a unique cytoplasmic domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	83259
Alternate Names	PCDH11 PCDH22protocadherin-22 PCDH-PC PCDH-Y PCDHYprotocadherin-11 Y-linked protocadherin 11 Y-linked protocadherin 22 Protocadherin on the Y chromosome Protocadherin prostate cancer protocadherin Y Protocadherin-11 Protocadherin-22 Protocadherin-PC