PCBP1 Products

Antibodies
PCBP1 Antibody (3D12)
PCBP1 Antibody (3D12)
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
PCBP1 Antibody
PCBP1 Antibody
NBP1-80455
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
PCBP1 Antibody (1G2)
PCBP1 Antibody (1G2)
H00005093-M01
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IF
Host: Mouse Monoclonal
Lysates
PCBP1 Overexpression Lysate ( ...
PCBP1 Overexpression Lysate (Native)
NBL1-14142
Applications: WB
Proteins
PCBP1 Recombinant Protein
PCBP1 Recombinant Protein
NBP2-23340
Species: Hu
Applications: PAGE
RNAi
PCBP1 RNAi
PCBP1 RNAi
H00005093-R01
Species: Hu

Description

PCBP1 is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq]

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 5093
Alternate Names
  • Alpha-CP1
  • Heterogeneous nuclear ribonucleoprotein E1
  • nucleic acid binding protein sub 2.3
  • poly(rC)-binding protein 1
  • heterogenous nuclear ribonucleoprotein X
  • hnRNP-X
  • heterogenous nuclear ribonucleoprotein E1
  • hnRNP-E1
  • alpha-CP1
  • HNRPX
  • hnRNP E1
  • HNRPE1
  • Nucleic acid-binding protein SUB2.3
  • poly(rC) binding protein 1

PTMs for PCBP1

Learn more about PTMs related to PCBP1.

Phosphorylation
Cleavage
Reduction
Hydroxylation
Methylation
Ribosylation
Cysteinylation

Bioinformatics Tool for PCBP1

Discover related pathways, diseases and genes to PCBP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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