PAK2 Products

Antibodies
PAK2 Antibody (3B5)
PAK2 Antibody (3B5)
NBP1-47542
Species: Hu, Mk
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
PAK2 Antibody
PAK2 Antibody
NBP1-76721
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PAK2 Antibody
PAK2 Antibody
NBP1-76720
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PAK2 Overexpression Lysate (D ...
PAK2 Overexpression Lysate (Denatu...
H00005062-T01
Applications: WB
PAK2 Overexpression Lysate (D ...
PAK2 Overexpression Lysate (Denatu...
H00005062-T02
Applications: WB
Proteins
PAK2 Recombinant Protein
PAK2 Recombinant Protein
P4741
Species: Hu
Applications: Func, PAGE
PAK2 Peptide
PAK2 Peptide
NBP1-76720PEP
Species: Hu
Applications: AC
PAK2 Peptide
PAK2 Peptide
NBP1-76721PEP
Species: Hu
Applications: AC
RNAi
PAK2 RNAi
PAK2 RNAi
H00005062-R02
Species: Hu

Description

p21-activated kinase 2 (PAK2) is a member of a family of serine/threonine protein kinase defined by their interaction with the small GTPases, Cdc42 and Rac (1-2). The PAK proteins can be essentially divided into two categories, groups I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK5 and PAK6), based on their structures (3). All six PAKs play an important role in diverse cellular processes, including cytoskeletal dynamics, growth/apoptotic signal transduction through MAP kinases, and regulation of transcription factors (4). The ubiquitous PAK-2 is unique among the PAK isoforms because it is also activated through proteolytic cleavage by caspases or caspase-like proteases (5). Full-length PAK-2 is localized in the cytoplasm, whereas the proteolytic PAK-2p34 fragment translocates to the nucleus. Activation of full-length PAK-2 stimulates cell survival, whereas proteolytic activation of PAK-2p34 is involved in programmed cell death (6).

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 5062
Alternate Names
  • p58
  • EC 2.7.11
  • p21-activated kinase 2
  • Gamma-PAK
  • PAK-2
  • serine/threonine-protein kinase PAK 2
  • p21 (CDKN1A)-activated kinase 2
  • gamma-PAK
  • PAKgamma
  • PAK65EC 2.7.11.1
  • S6/H4 kinase
  • p21 protein (Cdc42/Rac)-activated kinase 2

Research Areas for PAK2

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase

Bioinformatics Tool for PAK2

Discover related pathways, diseases and genes to PAK2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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