PAFAH1B2 Products

Description

Platelet-activating factor (PAF) is a biologically active phospholipid with diverse biologic effects. PAF is degraded to inactive products by hydrolysis of the acetyl group at the sn2 position to produce the biologically inactive products LYSO PAF and acetate. This reaction is catalyzed by PAF acetylhydrolase (PAFAH). The various monomeric and multimeric forms of the enzyme are composed of alpha, beta, and gamma PAFAH subunits. The catalytic activity of the enzyme resides in the beta and gamma subunits, whereas the alpha subunit has regulatory activity. Trimer formation is not essential for the catalytic activity.

Bioinformatics

Entrez	5049 Human 18475 Mouse 64189 Rat
Product By Gene ID	5049
Alternate Names	EC 3.1.1.47 intracellular platelet-activating factor acetylhydrolase alpha 2 subunit PAF acetylhydrolase 30 kDa subunit PAF-AH 30 kDa subunit PAFAH subunit beta PAF-AH subunit beta PAF-AH1b alpha 2 subunit PAFAHB platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) platelet-activating factor acetylhydrolase IB subunit beta platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa)

Research Areas for PAFAH1B2

Find related products by research area and learn more about each of the different research areas below.

Cancer
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