PA28 Activator gamma Subunit/PSME3 Products

Antibodies
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
Species: Hu, Mu, Rt, Chicken, Primate, Porcine
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
NBP1-83063
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
NBP1-54587
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
H00010197-T01
Species: Hu
Applications: WB
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
NBL1-14909
Applications: WB
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
NBP2-05019
Applications: WB
Proteins
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
NBP1-83063PEP
Species: Hu
Applications: AC
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
NBP1-72541
Species: Hu
Applications: PAGE
RNAi
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
H00010197-R01
Species: Hu
Applications: RNAi, RNAi SP
PA28 Activator gamma Subunit/ ...
PA28 Activator gamma Subunit/PSME3...
H00010197-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 10197
Alternate Names
  • REG-gamma
  • 11S regulator complex subunit gamma
  • PA28g
  • Proteasome activator 28 subunit gamma
  • proteasome activator complex subunit 3
  • Activator of multicatalytic protease subunit 3
  • proteasome activator 28-gamma
  • REG-GAMMA
  • Ki antigen
  • PA28-gamma
  • 11S regulator complex gamma subunit
  • Ki
  • PA28GKi nuclear autoantigen
  • PA28gamma
  • proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

Pathways for PA28 Activator gamma Subunit/PSME3

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Proteolysis
Localization
Dna Damage Checkpoint
Cognition
Catabolic Process

Research Areas for PA28 Activator gamma Subunit/PSME3

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Immune System Diseases
Immunology
Neuroscience
Stem Cell Markers
Ubiquitin Proteasome Pathway

PTMs for PA28 Activator gamma Subunit/PSME3

Learn more about PTMs related to PA28 Activator gamma Subunit/PSME3.

Phosphorylation
Cleavage

Bioinformatics Tool for PA28 Activator gamma Subunit/PSME3

Discover related pathways, diseases and genes to PA28 Activator gamma Subunit/PSME3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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