p19ARF/CDKN2A Products

p19ARF/CDKN2A Antibody (12-A1 ...
p19ARF/CDKN2A Antibody (12-A1-1)
Species: Mu, Ha(-), Hu(-)
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rat Monoclonal


p19ARF (mouse) and p14ARF (human) has become an important player in cell cycle regulation. In mice, tumor suppressor effects appear to be mediated by interactions between p19ARF and the p53 tumor suppressor protein. p19ARF counters uncontrolled proliferation and oncogenic signals in p53 dependent pathways. Proteins encoded by the INK4a/ARF locus also play a role in Abelson virus transformation. Both p16INK4a and p19ARF are expressed in many cells as they emerge from the apoptotic crisis that characterizes the transformation process. p19ARF is an important part in cellular defense against transforming signals from the Abl oncoprotein, providing direct evidence that the p19ARF-p53 regulatory loop plays an important role in lymphoma induction.


Uniprot Mouse
Product By Gene ID 12578
Alternate Names
  • MTS1
  • Pctr1
  • p19ARF
  • p19<ARF>
  • ARF-INK4a
  • INK4a-ARF
  • Ink4a/Arf
  • p16(INK4a)
  • CDK4I
  • alternative reading frame
  • CDKN2A
  • cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4)
  • cyclin-dependent kinase inhibitor 2A, isoform 3
  • cyclin-dependent kinase inhibitor 2A, isoforms 1/2
  • cyclin-dependent kinase inhibitor protein
  • mitochondrial smARF'
  • p19Arf
  • p19ARF
  • p19
  • p16INK4A
  • p16INK4a
  • p16-INK4a
  • p16
  • p16-INK4
  • p14
  • p14ARF
  • INK4a
  • cyclin-dependent kinase inhibitor 2A
  • P16
  • Cyclin-dependent kinase 4 inhibitor A
  • P19
  • INK4
  • P16INK4A
  • ARF

Research Areas for p19ARF/CDKN2A

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Cell Biology
Cell Cycle and Replication
Chromatin Research
DNA Repair
MAP Kinase Signaling
p53 Pathway
Transcription Factors and Regulators
Tumor Suppressors

Bioinformatics Tool for p19ARF/CDKN2A

Discover related pathways, diseases and genes to p19ARF/CDKN2A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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