FUNCTION: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. BIOPHYSICOCHEMICAL PROPERTIES: Absorption: Abs(max)=530 nm SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: The three color pigments are found in the cone photoreceptor cells. PTM: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region. DISEASE: Defects in OPN1MW are the cause of partial colorblindness deutan series (CBD); also called deuteranopia.
