NUP98 Products

Antibodies
NUP98 Antibody
NUP98 Antibody
NB100-93325
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
NUP98 Antibody
NUP98 Antibody
NB100-93327
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
NUP98 Antibody
NUP98 Antibody
NBP2-57805
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Antibody Pairs
NUP98 Antibody Pair
NUP98 Antibody Pair
H00004928-PW1
Species: Hu
Applications: WB, IP
Lysates
NUP98 Overexpression Lysate ( ...
NUP98 Overexpression Lysate (Denat...
H00004928-T02
Species: Hu
Applications: WB
NUP98 Overexpression Lysate ( ...
NUP98 Overexpression Lysate (Denat...
H00004928-T03
Species: Hu
Applications: WB
Proteins
Recombinant Human NUP98 Prote ...
Recombinant Human NUP98 Protein
H00004928-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human NUP98 Prote ...
Recombinant Human NUP98 Protein
H00004928-Q01
Species: Hu
Applications: WB, ELISA, PA
NUP98 Recombinant Protein Ant ...
NUP98 Recombinant Protein Antigen
NBP2-57805PEP
Species: Hu
Applications: AC
RNAi
NUP98 RNAi
NUP98 RNAi
H00004928-R02
Species: Hu
Applications: RNAi, RNAi SP
NUP98 RNAi
NUP98 RNAi
H00004928-R04
Species: Hu
Applications: RNAi, RNAi SP
NUP98 RNAi
NUP98 RNAi
H00004928-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kD nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kD precursor protein. This cleavage results in the 98 kD nucleoporin as well as a 96 kD nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kD nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq]

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4928
Alternate Names
  • ADAR2
  • NUP196
  • nuclear pore complex protein Nup98-Nup96
  • ADIR2
  • GLFG-repeat containing nucleoporin
  • nucleoporin 98kD
  • NUP96
  • Nup98-Nup96
  • nucleoporin 98kDa

Research Areas for NUP98

Find related products by research area and learn more about each of the different research areas below.

Cancer
Mitotic Regulators

Bioinformatics Tool for NUP98

Discover related pathways, diseases and genes to NUP98. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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