Nuclear Pore Complex Protein Nsp1p Products

Nuclear Pore Complex Protein ...
Nuclear Pore Complex Protein Nsp1p...
Species: Ye
Applications: WB
Host: Mouse Monoclonal


The Nuclear pore complex (NPC) has a molecular mass of approx. 125 KDa in vertebrates and contains about 50 or more different proteins. The NPC spans the dual membrane of the the nuclear envelope (NE) and acts as a gateway for macromolecular traffic between the cytoplasm and the nucleus. The basic framework of the NPC consists of a central core with a ring-spoke structure exhibiting 8 fold radial symmetry. From this central ring 50 to 100 nm fibrils extend into the nucleoplasm and the cytoplasm. The NPC is in turn anchored in the NE by the nuclear lamina, a meshwork of lamins and lamin-associated proteins that forms a 15 nm thick fibrous structure between the inner nuclear membrane and peripheral chromatin. A number of proteins called nucleoporins have been localized to discrete regions of the NPC and are often used as markers for this compartment, e.g. Nup153. Approximately half of the nucleoporins (or Nups) contain a phenyalanine-glycine repeat motif (FG repeat), which may be diagnostic for proteins playing a role in nuclear transport.


Alternate Names
  • 107 kDa nucleoporin
  • NUP98
  • NUP84
  • NUP155
  • NUP153
  • NUP107
  • NUP 84
  • NUP 107
  • Nucleoporin Nup107
  • Nucleoporin 107kDa
  • Nuclear pore complex protein Nup107
  • NPC proteins