NTAN1 Products

Antibodies
NTAN1 Antibody
NTAN1 Antibody
NBP2-15046
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
NTAN1 Overexpression Lysate ( ...
NTAN1 Overexpression Lysate (Native)
NBL1-13829
Applications: WB
NTAN1 Overexpression Lysate ( ...
NTAN1 Overexpression Lysate (Denat...
H00123803-T01
Species: Hu
Applications: WB
Proteins
NTAN1 Recombinant Protein
NTAN1 Recombinant Protein
H00123803-P01
Species: Hu
Applications: WB, ELISA, PA

Description

MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 beta1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissues. MECA-79 antibody reacts with mouse, human and many other species PNAd and blocks L-selectin-dependent lymphocyte adhesion in vitro and in vivo.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 123803
Alternate Names
  • PNAA
  • EC 3.5.1.-
  • Protein NTN-amidase
  • protein N-terminal asparagine amidohydrolase
  • Protein NH2-terminal asparagine deamidase
  • N-terminal asparagine amidohydrolase
  • Protein NH2-terminal asparagine amidohydrolase
  • DKFZp666E058
  • Protein N-terminal Asn amidase
  • PNAD
  • N-terminal asparagine amidase

Pathways for NTAN1

View related products by pathway and learn more about each of the pathways below.

Long-term Memory
Social Behavior
Associative Learning
Conjugation
Localization

Research Areas for NTAN1

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for NTAN1

Learn more about PTMs related to NTAN1.

Deamidation

Bioinformatics Tool for NTAN1

Discover related pathways, diseases and genes to NTAN1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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