NRXN1 Products

Description

Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible. [provided by RefSeq]

Bioinformatics

Uniprot	NM_138735 Human NP_001129131 Human NP_004792 Human NP_004792.1 Human Q9ULB1 Human
Product By Gene ID	9378
Alternate Names	DKFZp313P2036 FLJ35941 KIAA0578Neurexin I-alpha neurexin 1 neurexin I Neurexin I-beta neurexin-1-alpha neurexin-1-beta PTHSL2