NGEF Products

Description

NGEF acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse. Upon activation by ephrin through EPHA4, the GEF activity swi

Bioinformatics

Uniprot	Q8N5V2 Human NP_062824 Human
Product By Gene ID	25791
Alternate Names	ephexin-1 EPHEXIN Eph-interacting exchange protein neuronal guanine nucleotide exchange factorARHGEF27

Diseases related to NGEF

Discover more about diseases related to NGEF.

Neoplasms
Insulin Resistance
Nervousness
Neoplasms, Experimental
Tissue Adhesions
Atherosclerosis
Erythropoietic Protoporphyria
Aortic Aneurysm, Abdominal
Carcinoma

Pathways for NGEF

View related products by pathway and learn more about each of the pathways below.

Axon Guidance
Reverse Transcription
Gastrulation
Regulation Of Growth
Muscle Cell Differentiation
Cell Motility
Receptor Clustering
Locomotion
Cell Differentiation
Rna Interference
Cell-cell Adhesion

PTMs for NGEF

Learn more about PTMs related to NGEF.

Phosphorylation

Bioinformatics Tool for NGEF

Discover related pathways, diseases and genes to NGEF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.