NFYC Products

Description

NFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.

Bioinformatics

Uniprot	AAH05003 Human CAI16533.1 Human NM_014223 Human NP_055038.2 Human Q13952 Human
Product By Gene ID	4802
Alternate Names	C subunit nuclear transcription factor Y, gamma

Diseases related to NFYC

Discover more about diseases related to NFYC.

Malignant Neoplasm Of Lung
Carcinoma
Malignant Neoplasms
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Non-small Cell Lung Carcinoma
Melanoma
Bare Lymphocyte Syndrome
Immunologic Deficiency Syndromes
Cardiovascular Diseases
Neoplasms
Severe Combined Immunodeficiency
Congenital Combined Immunodeficiency
Squamous Cell Lung Carcinoma

Pathways for NFYC

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Regulation Of Cell Cycle
Cell Proliferation
Immune Response

PTMs for NFYC

Learn more about PTMs related to NFYC.

Phosphorylation

Bioinformatics Tool for NFYC

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