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NFkB p50 (NLS) Products

Inhibitors
NFkB p50 (NLS) Inhibitor Pept ...
NFkB p50 (NLS) Inhibitor Peptide Set
NBP2-29323
Functional (Inhibition) NFkB p50 (NLS) Inhibitor Peptide Set
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
Applications: Inhibition Activity
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We have 1 NFkB p50 (NLS) Inhibitor

Description

The NLS sequence is required for nuclear translocation of NF-kB p50. In stimulated cells, NF-kB is in the cytoplasm in an inactive form and the NLS is masked. The degradation of IkBalpha during NF-kB signaling unmasks the NLS of NF-kB subunits and NF-kB is translocated to the nucleus. The p50 inhibitory peptide contains the p50 NLS sequence (VQRKRQKLM) and blocks the intracellular recognition mechanism for the NLS present on p50. Consequently p50 nuclear translocation is blocked.

Bioinformatics

Product By Gene ID 4790
Alternate Names
  • CVID12
  • EBP-1
  • KBF1
  • NFkappaB
  • NF-kappaB
  • NF-kappa-B1
  • NFKB1
  • NF-kB1
  • NFKB-p105
  • NFKB-p50
  • nuclear factor kappa B subunit 1
  • p105
  • P50