Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Description
NAE1 is encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Bioinformatics
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
8883 |
Alternate Names |
- A-116A10.1
- amyloid beta precursor protein binding protein 1
- amyloid beta precursor protein binding protein 1, 59kDa
- Amyloid beta precursor protein-binding protein 1, 59 kDa
- amyloid beta precursor protein-binding protein 1, 59kD
- Amyloid protein-binding protein 1
- APPBP1APP-BP1
- NEDD8 activating enzyme E1 subunit 1
- NEDD8-activating enzyme E1 regulatory subunit
- NEDD8-activating enzyme E1 subunit
- protooncogene protein 1
- Proto-oncogene protein 1
- ula-1
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Research Areas for NEDD8 Activating Enzyme (APPBP1/UBA3)
Find related products by research area and learn more about each of the different research areas below.
Apoptosis