Ndufs4 Products

Description

Ndufs4 encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.

Bioinformatics

Uniprot	AAH05270 Human AAH05270.1 Human NM_002495 Human NP_002486 Human NP_002486.1 Human
Product By Gene ID	4724
Alternate Names	AQDQ AQDQmitochondrial CI-18 kDa NADH dehydrogenase (ubiquinone) Fe-S protein 4 (18kD) (NADH-coenzyme Qreductase) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Qreductase) NADH-coenzyme Q reductase, 18-KD NADH-ubiquinone oxidoreductase 18 kDa subunit